an insult used to describe a middle-aged white woman, who either says or does something that inconveniences an individual. The back-story and other relevant context are insignificant to the speaker, as making a cheap joke to gain Twitter ‘brownie points’ is all that matters.
Ex. “So I was yelling “BLACK LIVES MATTER” in the middle of a grocery store produce section, when a Karen pushed me aside so she can grab a her apples.”